Synergistic activation of the HTLV1 LTR Ets-responsive region by transcription factors Ets1 and Sp1.
نویسندگان
چکیده
منابع مشابه
Regulation of angiogenesis by ETS transcription factors.
Transcription factors of the ETS family are important regulators of endothelial gene expression. Here, we review the evidence that ETS factors regulate angiogenesis and briefly discuss the target genes and pathways involved. Finally, we discuss novel evidence that shows how these transcription factors act in a combinatorial fashion with others, through composite sites that may be crucial in det...
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We recently demonstrated that members of the c-ets proto-oncogene family, Ets1 and Ets2, are sequence-specific transcriptional activators of the human T-lymphotropic virus type I (HTLV-I) long terminal repeat (LTR). We now report that the HTLV-I LTR contains two distinct Ets1-responsive regions, ERR-1 and ERR-2. Expression of Ets1 with reporter plasmids containing ERR-1 or ERR-2 upstream of a b...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 1993
ISSN: 0261-4189
DOI: 10.1002/j.1460-2075.1993.tb05758.x